This paper is published in Volume 3, Issue 7, 2018
Area
Total Synthesis, Spectroscopy and Antimicrobial Drugs.
Author
Dr Jigar Patel
Org/Univ
SSR College of Arts, Science, and Commerce, Silvassa, Dadra and Nagar Haveli, India
Pub. Date
03 July, 2018
Paper ID
V3I7-1139
Publisher
Keywords
Furocoumarins, 4-Hydroxy coumarins, Nef reaction, Antimicrobial activity

Citationsacebook

IEEE
Dr Jigar Patel. Synthesis, characterization and antimicrobial screening of some furofused coumarines, International Journal of Advance Research, Ideas and Innovations in Technology, www.IJARnD.com.

APA
Dr Jigar Patel (2018). Synthesis, characterization and antimicrobial screening of some furofused coumarines. International Journal of Advance Research, Ideas and Innovations in Technology, 3(7) www.IJARnD.com.

MLA
Dr Jigar Patel. "Synthesis, characterization and antimicrobial screening of some furofused coumarines." International Journal of Advance Research, Ideas and Innovations in Technology 3.7 (2018). www.IJARnD.com.

Abstract

The synthesis of 3 -(1'- phenyl- 3'-aryl -1H-pyrazol -4'-yl) furo[3,2-c]coumarins (4a-f) and 2-methyl-3-(1'–phenyl-3'-aryl-1H-pyrazol-4'-yl)furo- [3,2-c]coumarins (5a-f) has been carried out by the reaction of various 4-hydroxy coumarins (1a-c) with appropriate 2-(1-phenyl-3-aryl-1H- pyrazol-4-yl)-1-nitro-ethenes (2a-b) and 1-(1-phenyl-3-aryl-1H-pyrazol-4-yl)-2-nitro propenes (3a-b) respectively in the presence of catalytic amount of piperidine in refluxing methanol. All the synthesized compounds (4a-f) and (5a-f) were screened for their antimicrobial activity.