Oral Erythroplakia is a Potentially malignant disorder. The disorder is strongly associated with substance abuse like smoking and smokeless Tobacco, Alcohol etc. it is most commonly associated with smoking tobacco. The present review article of oral Erythroplakia introduces definitions, clinical and Histopathological diagnostic features and short management chart of oral Erythroplakia which provides an easy key to diagnose and differentiate lesion by medicine specialist, ENT surgeon, Oral Surgeon etc.