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Analytical method development and validation for the estimation of chlorthalidone and atenolol by RP-HPLC

Separation of Atenolol and Chlorthalidone was successfully achieving thermal, C18, 250X4.6mm, 5µm, or equivalent in an isocratic mode utilizing 0.1M KH2PO4: Methanol (65:35) at a flow rate of 1.0ml/min and elute was monitored at 256nm, with a retention time of 3.346 and 3.931 minutes for Atenolol and Chlorthalidone respectively. The method was validated and their response was found to be linear in the drug concentration range of 50µg/ml to150 µg/ml for Atenolol and 50µg/ml to150 µg/ml for Chlorthalidone. The values of the correlation coefficient were found to 0.999 for Atenolol and 0.999 for Chlorthalidone respectively. The LOD and LOQ for Atenolol were found to be 0.110 and 0.366 respectively. The LOD and LOQ for Chlorthalidone were found to be 0.0818 and 0.2728 respectively. This method was found to be a good percentage recovery for were found to be 100 and 100 respectively indicates that the proposed method is highly accurate. The specificity of the method shows good correlation between retention times of standard with the sample so, the method specifically determines the analyte in the sample without interference from excipients of tablet dosage forms. The method was extensively validated according to ICH guidelines for Linearity, Accuracy, Precision, Specificity, and Robustness.

Published by: Rama Devi G., K. Nagaraju

Author: Rama Devi G.

Paper ID: V3I10-1142

Paper Status: published

Published: October 31, 2018

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Research Paper

Nutritional status of institutionalized elderly population of Lucknow city

The proportion of people aged 60 years is growing faster than any other age group in almost every country. The nutritional status has proven to decrease with age which affects the general health as well as oral health. The Mini Nutritional Assessment (MNA) designed by B. Vellas is a clinical assessment tool for grading nutritional status. A cross-sectional study was conducted to assess the nutritional status of the institutionalized elderly population of Lucknow city. All the population from all the old age homes of Lucknow city who were more than or equal to 60 years were included in the study. Mini Nutritional Assessment-Short Form (MNA-SF) was used to record the nutritional status. The sample included 287 elderly, of which 104 (36.2%) consisted of males, and 183 (63.8%) were females. The MNA score of the study sample showed that 78% were malnourished, 22% were at risk of malnutrition. We observed a high percentage of female (54.70%) were malnourished than male (23.30%). Within the age group of 60-65, 66-70, 71-75, 76-80, >80, we observed higher percentage of malnourished elderly population 21 (7.30%), 51 (17.80%), 61 (21.30%), 36 (12.50%), 55 (19.20%) respectively. 100% of the subjects showed nutritional deficits, a high percentage of females were more malnourished than males.

Published by: Dr. Ankita Singh, Dr. Anuradha P., Dr. Manu Narayan

Author: Dr. Ankita Singh

Paper ID: V3I10-1185

Paper Status: published

Published: October 31, 2018

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Review Paper

A review on challenges and opportunities in Blockchain Technology

The Blockchain is a decentralized exchange and information association improvement grew first for Bitcoin cryptographic money. A Blockchain is basically a passed on database of records, or open record everything considered or motorized occasions that have been executed and shared among taking interest parties. Each exchange the comprehensive network record is certified by an assertion of a greater bit of the people in the structure. Once entered, data can never be deleted. The Blockchain contains a certain and clear record of each and every exchange whenever made. Bitcoin, the decentralized appropriated electronic money, is the most standard blueprint that utilization Blockchain advancement. The modernized cash Bitcoin itself is outstandingly sketchy at any rate the central Blockchain headway has worked consummately and discovered wide grouping of utilization in both monetary and non-budgetary world. The fervor for Blockchain advancement has been developing since the considering was established in 2008. The explanation for the energy for Blockchain is its focal properties that give security, namelessness and information steadfastness with no outcast alliance accountable for the exchanges, and appropriately it makes dazzling examination zones, particularly from the point of view of particular difficulties and repressions. In this examination, we have composed a consider mapping study with the objective of a social event on all basic research on Blockchain advancement. We will most likely understand the stream research subjects, inconveniences and future headings with respect to Blockchain progression from the particular point of view.

Published by: Urvi Dilipkumar Rajguru

Author: Urvi Dilipkumar Rajguru

Paper ID: V3I10-1166

Paper Status: published

Published: October 30, 2018

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Research Paper

Application of operations research in financial markets and marketing

This paper reviews the Applications of Operations Research in Financial Markets and Marketing. It shows how OR has become an interface for such dynamic Fields. Finance can be described as the science of money management. It is quantitative in nature. Marketing is the study and management of exchange relationships (Bagozzi, Richard, 1975). It is more behavioural and innovative in nature. However, in this paper, we see how similar OR techniques can be applied to two contrasting fields.

Published by: Maria Shaikh, Manvi Mehta, Miloni Shah, Mehnaz Ali, Shivam Mahana

Author: Maria Shaikh

Paper ID: V3I10-1183

Paper Status: published

Published: October 27, 2018

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Research Paper

Auction of mines in India

The concept of the auction came right around the time economists saw the opportunity between the gap of demand and supply as well as the value attached to some items. Economists generally like to believe that the auction originates from the concept of scarcity that is the death of a certain required commodity in the required amount. Resources are limited but the population grows, opening the biggest market in the whole wide world up for auction- resources. The land has its own format of adjusting its price according to market forces. But mineral and other resources need to be allocated not just on the basis of market forces but other factors like the population, its density, the local environment, etc. thus came into the picture the concept of controlled auctions by the government who usually own the resources. As most governments do not allow private sectors to own such important resources, the property themselves weren’t auctioned but rather leased out on a contract basis. In South Africa, the debate on sharing mineral wealth between stakeholders can be traced back to the mine labor disputes of the 1920s and 1940s, and the 1955 freedom charter (competitive resource tenders as an option for mining rights allocation in South Africa, November 2013). Around the world, the auctioning of mines started in the 1950s.

Published by: Janki Hariani, Harshita Malladi, Jash Mehta, Manthan Dedhia, Kaushik Bhutka

Author: Janki Hariani

Paper ID: V3I10-1182

Paper Status: published

Published: October 25, 2018

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Research Paper

Use of operations research in football

This paper presents the use of operations research in football and the FIFA world cup. Football is getting popular day by day and so is the use of Operations Research in it. Operations Research is used in football for designing football, designing goal lines and goal posts, proper selection and distribution of teams, knowing the probability of win-lose and optimizing the overall costs. There are a few limitations of Operations Research like hiring an Operations Research expert for analysing. The implementation is also a drawback. But, Operations Research has proved very useful for the football industry.

Published by: Janki Hariani, Harshita Malladi, Jash Mehta, Manthan Dedhia, Kaushik Bhutka

Author: Janki Hariani

Paper ID: V3I10-1181

Paper Status: published

Published: October 25, 2018

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Review Paper

An intelligent human life safety system

An electric shock is due to the electric leakage which results from a lot of damage to appliances and also causes injury to humans even leads to death. Forty-two percent of total fires occur due to electrical sources and eight percent of deaths that occurs in Indian factories are due to electrocution. When a part of the body gets conduct between two conductors or between a conductor and a grounding source, it forms a complete circuit and results in electrical shock. Each year, the result of electrical accidents is more than 12,306 crores in property damage in home and industry. To overcome these problems, our project gives a better solution. Electric shock or accidents can be prevented by the proposed system. Whenever the human is electrocuted, the electric shock is detected and then the sensed signal is transmitted to the microcontroller using the RF transmitter and receiver. The microcontroller is used to detect the signal from RF receiver and then the microcontroller passes the control to relay which will trip the main board. Then the alarm sounds as it is alert for the nearby users. It also gives the alert message to the authorized person using GSM. With the help of IoT technology, the exact location and time information can be found and the electric shock information is stored for data records. This proposed system helps to find the electric shock and to avoid the untoward incident happening in the home or industry and saves the human life.

Published by: Abinaya S., Ramya E., Hariharan D., Gowtham C.

Author: Abinaya S.

Paper ID: V3I10-1170

Paper Status: published

Published: October 25, 2018

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Research Paper

Analysis the characteristic behaviour of quarry and furnace waste kerb stone

Quarry Dust and the crushed stone as alternative aggregates for concrete production for low-cost housing since it is clear that the rising cost of concrete materials coupled with environmental degradation has impaired the construction industry. The following tests were carried out to determine the physical properties of these materials; density tests, silt content, water absorption, sieve analysis, specific gravity, flakiness index and aggregate crushing value. The research was conducted by testing concrete cylinder and cubes specimens at ages of 7, 14 and 28 days concrete with concrete mix ratios 1:1.5:3 with a target strength of 25N/mm2 and 1:2:4 with a target strength of 20N/mm2. Samples of concrete specimens were made using varying contents of quarry dust and laterite as fine aggregate. India is a developing contrary due to there is a huge need for infrastructure that is why construction is very important. In the construction the main material his problem we are making Kerb stone using this. This Kerb stone is stronger economical and effective than the clay Kerb stone. This process also helps in converting the industrial waste material into quality building material.

Published by: Sandeep, Nitin Thakur

Author: Sandeep

Paper ID: V3I10-1180

Paper Status: published

Published: October 24, 2018

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Review Paper

A review on analysis the characteristic behaviour of quarry and furnace waste kerb stone

Quarry Dust and the crushed stone as alternative aggregates for concrete production for low-cost housing since it is clear that the rising cost of concrete materials coupled with environmental degradation has impaired the construction industry. The following tests were carried out to determine the physical properties of these materials; density tests, silt content, water absorption, sieve analysis, specific gravity, flakiness index and aggregate crushing value. The research was conducted by testing concrete cylinder and cubes specimens at ages of 7, 14 and 28 days concrete with concrete mix ratios 1:1.5:3 with a target strength of 25N/mm2 and 1:2:4 with a target strength of 20N/mm2. Samples of concrete specimens were made using varying contents of quarry dust and laterite as fine aggregate. India is a developing contrary due to there is a huge need for infrastructure that is why construction is very important. In the construction the main material his problem we are making Kerb stone using this. This Kerb stone is stronger economical and effective than the clay Kerb stone. This process also helps in converting the industrial waste material into quality building material. In this study, the fine and coarse aggregates were completely replaced by Quarry & Furnace Waste aggregates in Quarry & Furnace Waste concrete. In the present study, we are making three types of Quarry & Furnace Waste Kerb stones in the different percentage of cement such as 3%, 5% and without cement. And after making these Kerb stones various tests were performed such as compressive strength test, water absorption test, efflorescence, weight test, structural test, and cost analysis and these results were compared with normal Kerb stones results.

Published by: Sandeep, Nitin Thakur

Author: Sandeep

Paper ID: V3I10-1179

Paper Status: published

Published: October 24, 2018

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Research Paper

Translations of the noble Qur’an

The Qur’an is the book of Allah the mighty, sent for the entire humanity. It is a miracle that has no match, the words of which has the depth of countless oceans and immensity of skies. Sent word by word with utmost sophistication and eloquence to our beloved Prophet Muhammadﷺ through the leader of angels Hazrat JibreelAS. The Qur’an has in total 114 Surat (chapters) with each chapter consisting few too many Ayats (verses). About the authenticity of the miraculous Qur’an Allah says in Surat 17 (Bani Israel) Ayat 88: Say, “If mankind and the jinn gathered in order to produce the like of this Qur’an, they could not produce the like of it, even if they were to each other assistants.” (17:88) The Qur’an is the constitution revealed by Allah to regulate and govern human life. It has the essence and knowledge of the entire conception by its creator. The Qur’an is the perfect and the only complete guide. We have witnessed changes and revisions in the sacred texts of other faiths but the inimitable quality of the Qur’an has reserved its place as it had in the days of Prophet Muhammadﷺ.

Published by: Fasil Barkat Dar

Author: Fasil Barkat Dar

Paper ID: V3I10-1178

Paper Status: published

Published: October 24, 2018

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