Background: Osteoarthritis of the knee is one of the common diseases, mainly affecting the articular cartilage of a synovial joint. Which results in pain, decreased proprioception, muscle weakness, and disability. Mulligan’s mobilization helps in relieving pain and improves ROM, but lacks in stability. Agility and perturbation exercises improve stability and proprioception but lack in the improvement of ROM. Mulligan’s mobilization and Agility and Perturbation exercises in combination can bring better outcome results. Purpose: The purpose of the study is to find out whether Mulligan’s mobilization MWM (Internal rotation glide) as an adjunct to Agility and Perturbation can bring better outcome in patients when compared to Mulligan’s alone. Methods: 60 patients were assigned to two groups 30 each group and subjects were selected by convenient sampling method. Group A with mulligan’s mobilization alone and group B SWD with Mulligan’s mobilization as an adjunct to Agility and Perturbation exercises. The treatment session was performed on alternate days for 6weeks. Each subject performed all the measurement with knee function assessed NPRS, knee ROM by Goniometer, Timed up and go scale (TUG) and WOMAC index. All outcome were tested at starting the day, week 3 and final week 6 of pre and post-treatment. Results: The group analysis was done for NPRS, TUG, ROM, WOMAC in the evaluation of knee function was done using independent ‘t’ test. Within the groups paired t-test used and showed statistically significant. Conclusion: It is concluded that Mulligan’s technique with Agility and perturbation exercises is a better treatment approach than Mulligan’s with conventional exercises.