Background: Primary open angle glaucoma is one of the major cause of blindness and it have only surgical treatment and lifelong use of medication. Hence many side effects arise. To overcome this, the drugless approach is in practice but the importance of Muscle Energy Technique (met) and Myofacial (MFR) Release is not explored. Objective: To determine the effectiveness of MET and MFR on primary open angle glaucoma in primary open angle glaucoma. Setting: Tertiary care teaching hospital Methods: 12 subjects with Primary open angle glaucoma was recruited through criteria based convenience sampling for the study. The age ranges from 15-30 years. MET and MFR was given to the subjects30 mins/day, six days/week for three weeks. Intraocular pressure was assessed with Tonometer as dependent variable by Ophthalmologist. Pre and post treatment intraocular pressure change is established. Result(s): Pre IOP and Post are 23.11±1.98 mmHg and Post IOP is 20.05±.1.42 mmHg respectively. The mean pre-post difference is 3.1± 1.9 mmHg with significance difference of p< 0.001. Conclusion: MET and MFR reduce intraocular pressure and relieve from other symptoms.