Background: The evaluation of intracranial granulomatous lesions with emphasis particularly on tuberculoma and neurocystecercosis. Intracranial granulomatous lesions especially tuberculosis and neurocysticercosis are potentially lethal diseases and therefore prompt diagnosis and treatment are imperative. Cysticercosis of the brain is a disease entity that is easily demonstrable by CT and is confined to the endemic areas in the majority of cases Aim: To identify and the role of computed tomography (CT) in diagnosing intracranial granulomatous lesions and to correlate the findings with clinical health care. Materials and methods: This study was done at Ganesh Shankar Vidyarthi Medical (GSVM) College, Kanpur, Uttar Pradesh, India during the period 2002 to 2003. The patients admitted with seizures were included after considering the exclusion of metabolic causes and infective causes. 50 cases of documented antecedent history suggestive of raised intracranial tension and seizure (focal or generalized) were evaluated and referred for CT scanning from outpatients department and in patients department in Lala Lajpat Rai (LLR) and associated hospitals and GSVM College, Kanpur, India. Results: We prospectively noted in our study that more than half of the patients with chronic granulomatous lesions presented with raised intracranial tensions. The seizure was one of the commonest presenting complaints in patients with neurocysticercosis diagnosis. A presumptive diagnosis of tuberculoma and neurocysticercosisis was based on clinical and other ancillary criteria. Associated family history and extracerebral tuberculosis are the important criteria for a presumptive diagnosis of tuberculoma. Solitary lesions were more frequent CT finding in both tuberculoma and neurocysticercosis. Majority of tuberculomas and neurocysticercosis observed were supratentorial in location, regardless of their clinical presentation. Lesions were isodense or hyperdense on plain CT scan showed peripheral enhancement with intravenous contrast injection. The lobulated masses represent coalesced small disc and rings forming a large tuberculoma. Conclusion: In our study, we have tried to evaluate intracranial granulomatous lesions with emphasis particularly on tuberculoma and neurocystecercosis.